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Berkeley | 2013 | Ph.D.
McGill University | 2008 | B.Sc.
Dr. Kronstad received her Ph.D in Microbiology from the University of Berkeley, California in 2013. She completed her postdoctoral fellowship at Stanford University in the Department of Medicine. She joined the faculty at Midwestern University in 2019 as an Assistant Professor.
College of Graduate Studies - AZ
College of Veterinary Medicine
Microbiology & Immunology
Biomedical Sciences (M.B.S.)
Medical Microbiology MICRG 1615/1616 & 1625/1626
Immunology MICRG 1553
Integrated Basic Sciences 1504-6/1513-15
Veterinary Microbiology II MICRG 1672
Immunology MICRG 1531
Vaccines represent the most efficient way to prevent disease with influenza A viruses (IAV) in humans and animals. Unfortunately, the generation of immunity represents a major hurdle of IAV vaccination. Natural killer and Dendritic cells are innate immune cell that traffic rapidly to the lung after infection and are critical for controlling IAV infection in both human and mouse models. However, the precise mechanisms used by IAV to evade or trigger activation of these cells remains unclear. To address these research questions, we use primary human immune cells harvested from blood and a panel of evolutionary distinct IAV strains. Using immunological techniques ‐ such as flow cytometry and ELISA ‐ and viral genetics, we seek to identify the precise viral genes, host pathways and immune signal involved at the interface of IAV infection and innate immunity. Students will be encouraged to develop an independent research project and present their data at scientific conferences.
Christof Seiler, Lisa M. Kronstad, Laura J. Simpson, Mathieu Le Gars, Elena Vendrame, Catherine A. Blish ,Susan P. Holmes. (2019) Uncertainty Quantification in Multivariate Mixed Models for Mass Cytometry. ArXiv. arXiv:1903.07976.
Lisa M. Kronstad, Christof Seiler, Rosemary Vergara, Susan P. Holmes, Catherine A. Blish. (2018) Differential induction of IFN-α and modulation of CD112 and CD54 expression governs the magnitude of NK cell IFN-γ response to influenza A viruses. J. Immuol. doi:10.4049/jimmunol.1800161
Lisa M. Kronstad, Kevin F. Brulois, Jae U. Jung, and Britt A. Glaunsinger. (2014) Reinitiation after Two Upstream Open Reading Frames Governs Expression of the ORF35-37 KSHV Polycistronic mRNA. J Virol. Jun;88(11):6512-8. doi: 10.1128/JVI.00202-14.
Lisa M. Kronstad, Kevin F. Brulois, Jae U. Jung, and Britt A. Glaunsinger. (2013) Dual Upstream Open Reading Frames Control Translation of a Herpesviral Polycistronic mRNA. PLoS Pathog 9(1): e1003156. doi: 10.1371/journal.ppat.1003156.
Lisa M. Kronstad and Britt A. Glaunsinger. (2012) Diverse Virus-Host Interactions Influence RNA-based Regulation during Gamma-Herpesvirus Infection. Curr. Opin. Microbiol. 15, 506–511. doi: 10.1016/j.mib.2012.05.010
Cecilia Quiroga, Lisa M. Kronstad, Christine Ritlop, Audrey Filion and Benoit Cousineau. (2011) Contribution of Base Pairing Interactions between Group II Intron Fragments during Trans-splicing in vivo. RNA. 2011 Vol. 17 (12). doi: 10.1261/rna.028886.111
American Association of Immunologists
American Society of Virology
College of Veterinary Medicine AREA Grant 2019-2020
NIH Institutional Training Grant, 5T32AI007290-29
A.P. Giannini Postdoctoral Fellowship
Outstanding Postdoctoral Mentor Award
NSERC Canada Post-Graduate Scholarship
Natural Sciences and Engineering Research Council (NSERC) Undergraduate Student Research Award